Luminex screening first vs. direct single antigen bead assays: Different strategies for HLA antibody
Interesting paper comparing two vendors' products. Their conclusion is:
Luminex screening failed to identify clinically relevant HLA antibodies, hampering DSA detection in patients with possible ABMR. Direct SAB testing should be the chosen strategy for post-transplantation monitoring, albeit direct SAB from the two existing manufacturers may diverge in as much as 50% of cases.
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